

Biocompatible Interference Screw
Osteotwin™ Interference Screw was designed to fulfill two core aims: provide appropriate mechanical properties necessary for ligament reconstruction whilst ensuring a regulated resorption and osteointegration to form architectural bone through hydrolysis.
Osteotwin™ Interference Screw videos
Increased Osteoconductivity with
Osteotwin™ Composite Interference Screw
Osteotwin™ Composite Interference Screw is composed of 75% PLDLLA + 25% BCP.
Osteotwin™ Composite Interference Screw provides the convenient ratio between the necessary mechanical resistance for the indication and the faculty to generate bone growth.
The addition of mineral charge in the polymer matrix increases the osteoconductivity of the implant. BCP (biphasic calcium phosphate) is an osteoconductive material known to promote bone ingrowth as the screw resorbs (Sharp et al. 2018; Debieux et al. 2016; Daculsi et al. 2011). The addition of BCP to PLDLLA interference screws used in ACL reconstruction reduces the speed of resorption while improving ossification, reducing tunnel widening and increasing cortical formation. The benefits of osteoconductive additives are more discernible in the tibia than in the femur (Barth J. et al., Orthopaedic Journal of Sports Medicine 4 (5), 2016).
Ongoing Clinical Study
Osteotwin™ Composite is a safe solution for ACL reconstruction, with no reported serious adverse events.
In order to consolidate our clinical data, we have launched, in collaboration with ATLANSTAT, two clinical trials to assess performance and safety of the composite and polylactic interference screws used in ACL reconstructions. The 56 participants of the clinical trial on Osteotwin™ Composite Interference Screw have already been recruited and we expect the first results by end of 2021. Recruitment is still ongoing for the second clinical trial on Osteotwin™ Polylactic Interference Screw. You can follow clinical study updates on ClinicalTrials.gov.
Canulated Interference Screw Design
The thread is specific to each screw diameter so as to systematically provide the maximum amount of contact between implant and bone.
Canulated Interference Screw Design
The thread is specific to each screw diameter so as to systematically provide the maximum amount of contact between implant and bone.

SPECIFIC DESIGN THREAD FOR OPTIMAL CONTACT

SMOOTH THREAD TO MINIMIZE DAMAGE ON LIGAMENT

GRADUATED TAPERED DESIGN TO OPTIMIZE TORQUE
Osteotwin™ Interference Screw Range
ACL SURGERY
The Osteotwin™ Interference Screw is intended for use for ligament/graft fixation within the osseous tunnel during knee ligament reconstruction. The specific design thread for each screw diameter allows maximum contact between implant and bone and makes Osteotwin™ screws more resistant to pull-out.

COMPOSITE INTERFERENCE SCREW Range | Size in mm: |
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![]() | 7x20 |
![]() | 7x25 |
![]() | 7x30 |
![]() | 8x20 |
![]() | 8x25 |
![]() | 8x30 |
![]() | 9x20 |
![]() | 9x25 |
![]() | 9x30 |
![]() | 10x25 |
![]() | 10x30 |
![]() | 11x35 |
COMPOSITE INTERFERENCE SCREW Range | Size in mm: |
---|---|
![]() | 7x20 |
![]() | 7x25 |
![]() | 7x30 |
![]() | 8x20 |
![]() | 8x25 |
![]() | 8x30 |
![]() | 9x20 |
![]() | 9x25 |
![]() | 9x30 |
![]() | 10x25 |
![]() | 10x30 |
![]() | 11x35 |
PUBLICATIONS
- G. Jouan, E. Goyenvalle, E. Aguado, R. Cognet, X. Bourges, F. Moreau and G. Daculsi.(2008) Key Engineering Marerials Vols. 361-363 Trans Tech Publications, Switzerland. PL DLLA calcium phosphate composite combined with Macroporous Calcium Phosphate Cement MCPC™ for new surgical technologies of resorbable osteosynthesis and Injectable bone substitute.
- G. Daculsi, D. Chappard, E. Aguado, G. Legeay, P. Layrolle and P. Weiss. (2008) Key Engineering Marerials Vols. 361-363, Multiphasic Biomaterials : A concept for Bone Substitutes developed in the “Pays de la Loire”.
- G. Daculsi. (2006) Advances in Science and Technology Vol.49, pp 9-13. Trans Tech Publications, Switzerland. Biphasic calcium phosphate Granules concept for Injectable and Mouldable Bone substitute.
- Daculsi G., Laboux O., Malard O., Weiss P. (2003). Journal of materials science: materials in medicine vol 14(3): 195-200. Current state of the art of biphasic calcium phosphate bioceramics.
- Daculsi G., Jegoux F., Layrolle P, in press 2008-1. In advanced Biomaterials: Fundamentals, Processing and Applications, John WILEY & Sons USA. The micro macroporous biphasic calcium concept for bone reconstruction and tissue engineering.
- Malard O., Gauthier H., Daculsi G Key engineering materials Vols 361-363 :pp1233-1236 (2008). In vivo demonstration of 2 types of microporosity on the kinetic of bone ingrowth and biphasic calcium phosphate bioceramics resorption.
- Nihouannen DL, Saffarzadeh A, Aguado E, Goyenvalle E, Gauthier O, Moreau F, Pilet P, Spaethe R, Daculsi G, Layrolle P. (2007) . J Mater Sci Mater Med. 2007 Feb;18(2):225-235. Osteogenic properties of calcium phosphate ceramics and fibrin glue based composites.
- Johannes Barth, Panagiotis Akritopoulos, Nicolas Graveleau, Renaud Barthelemy, Cécile Toanen and Mo Saffarini (2016) in The Orthopaedic Journal of Sports Medicine : Efficacy of Osteoconductive Ceramics in Bioresorbable Screws for Anterior Cruciate Ligament Reconstruction.
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