Biomatlante Interference Screw

Biocompatible Interference Screw

Osteotwin™ Interference Screw was designed to fulfill two core aims: provide appropriate mechanical properties necessary for ligament reconstruction whilst ensuring a regulated resorption and osteointegration to form architectural bone through hydrolysis.

Osteotwin™ Interference Screw videos

Increased Osteoconductivity with
Osteotwin™ Composite Interference Screw

Osteotwin™ Composite Interference Screw is composed of 75% PLDLLA + 25% BCP.

Osteotwin™ Composite Interference Screw provides the convenient ratio between the necessary mechanical resistance for the indication and the faculty to generate bone growth.

The addition of mineral charge in the polymer matrix increases the osteoconductivity of the implant. BCP (biphasic calcium phosphate) is an osteoconductive material known to promote bone ingrowth as the screw resorbs (Sharp et al. 2018; Debieux et al. 2016; Daculsi et al. 2011). The addition of BCP to PLDLLA interference screws used in ACL reconstruction reduces the speed of resorption while improving ossification, reducing tunnel widening and increasing cortical formation. The benefits of osteoconductive additives are more discernible in the tibia than in the femur (Barth J. et al., Orthopaedic Journal of Sports Medicine 4 (5), 2016).

Ongoing Clinical Study

Osteotwin™ Composite is a safe solution for ACL reconstruction, with no reported serious adverse events.

In order to consolidate our clinical data, we have launched, in collaboration with ATLANSTAT, two clinical trials to assess performance and safety of the composite and polylactic interference screws used in ACL reconstructions. The 56 participants of the clinical trial on Osteotwin™ Composite Interference Screw have already been recruited and we expect the first results by end of 2021. Recruitment is still ongoing for the second clinical trial on Osteotwin™ Polylactic Interference Screw. You can follow clinical study updates on ClinicalTrials.gov.